Abstract Background On mammography many cancers may be missed even in retrospect either due to the breast density, the small size of the tumor or the subtle signs of cancer that are imperceptible.We aimed to compare the sensitivity of artificial intelligence (AI) to that of digital mammography in the detection of different types of breast cancer.Al
Multi-omics analyses of CD276 in pan-cancer reveals its clinical prognostic value in glioblastoma and other major cancer types
Abstract Background CD276 (also known as B7-H3) is one of the most important immune checkpoints of the CD28 and B7 superfamily, and its abnormal expression is closely associated with various types of cancer.It has been shown that CD276 is able to inhibit the function of T cells, and that this gene may potentially be a promising immunotherapy target
Basic mechanisms of platelet receptor shedding
Proteolytic shedding of the extracellular ectodomain of platelet receptors provides a key mechanism for irreversible loss of ligand-binding capacity, and for regulating platelet function in health and disease.Platelets derived from megakaryocytes are small anucleate cells in peripheral blood, with the ability to rapidly adhere, become activated, an
Data-based flooding fault diagnosis of proton exchange membrane fuel cell systems using LSTM networks
Flooding fault diagnosis is critical to the stable and Soup Bowls efficient operation of fuel cells, while the on-board embedded controller has limited computing power and sensors, making it difficult to incorporate the complex gas-liquid two-phase flow models.Then in fuel cell system for cars, the neural network modeling is usually regarded as an
Alveolar macrophage-derived gVPLA2 promotes ventilator-induced lung injury via the cPLA2/PGE2 pathway
Abstract Background Ventilator-induced lung injury (VILI) is a clinical complication of mechanical ventilation observed in patients with acute respiratory distress syndrome.It is Pool Coping characterized by inflammation mediated by inflammatory cells and their secreted mediators.Methods To investigate the mechanisms underlying VILI, a C57BL/6J mou